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The principal cytochrome P450 isoenzyme associated appears to generally be CYP2E1, with CYP1A2 and CYP3A4 as supplemental pathways. Around 85% of an oral dose appears inside the urine inside of 24 hours of administration, most given that the glucuronide conjugate, with modest quantities of other conjugates and unchanged drug (see OVERDOSAGE) for to